PharmD · Indiana
Collaborative Practice Agreement for Pharmacists in Indiana
Yes, a written physician agreement is required. Indiana calls it a Written Collaborative Practice Protocol.
Indiana's is a narrow protocol-based 'drug regimen adjustment' tier (IC 25-26-16), not a broad collaborative-practice-agreement model. Outside hospitals, the pharmacist must be employed by or under contract with a physician, physician group, or outpatient clinic AND under 'direct supervision' (IC 25-26-16-4.5) — so an ordinary community pharmacist cannot access it. The pharmacist may only adjust therapy for a condition the patient has already seen a physician for.
What the collaboration must look like
The rules the physician relationship has to follow. Each fact comes from the statute or board rule listed under sources.
Proximity
pharmacist practicing outside a hospital: Available remotely (no on-site requirement)
IC 25-26-16-4.5(b) defines 'direct supervision' as the supervising physician, qualifying APRN, or PA with delegated prescriptive authority being 'readily available to consult with the pharmacist while the protocol services are being provided.' Coded TELECOMMUNICATION: it is a live-availability standard, not a physical-presence or mileage one. Note it binds DURING the service, which is tighter than a general on-call obligation.
pharmacist practicing in a hospital: Available remotely (no on-site requirement)
IC 25-26-16-4 applies instead: the pharmacist is 'supervised by a physician as required under the protocols of the facility.' The statute sets no proximity standard of its own — the facility's protocol does. Coded TELECOMMUNICATION as the closest available value; treat it as 'not codified at the state level' rather than as an affirmative finding that remote availability suffices.
Supervision ratio
Not codified — no cap on file
Chart review
Not codified — left to the agreement
Meeting cadence
Annually
IC 25-26-16-7: a protocol developed under the chapter 'must be reviewed at least annually.' A protocol-review cadence, not a chart-review quota — Indiana codifies no percentage for pharmacists. IC 25-26-16-6 adds a real administrative friction point: except for adding or deleting authorized practitioners and pharmacists, ANY modification to a written protocol 'requires the initiation of a new protocol' rather than an amendment. IC 25-26-16-8 separately requires documentation showing 'adequate, consistent, and regular communication' with the authorizing practitioner, and immediate entry of any regimen change in the patient's medical record — but sets no frequency for either.
Prescriptive authority
Covered by the practice agreement · no controlled-substance authority
IC 25-26-16 is silent on controlled substances and DEA scheduling entirely — this is genuine statutory silence, not merely an unresolved search. Coded False as an INFERENCE from the 'physician-first' structure, the same reading applied to Texas's pharmacist entry; flagged as an inference rather than an explicit statutory prohibition. SEPARATE AND UNVERIFIED: Indiana pharmacists also hold narrow independent authority outside IC 25-26-16 — immunizations under a standing order, prescription, or protocol (IC 25-26-13-31.2), and reportedly self-administered hormonal contraceptives, which an April 2026 Board of Pharmacy final rule (856 IAC, LSA #25-798) is said to have moved from a health-commissioner standing order to a statewide protocol with the pharmacist as prescriber of record. The IARP register page for that rule returned an empty SPA shell; the description is secondary-sourced only and is NOT relied on for any coded rule here.
Written agreement
Required
Required only for the protocol-based drug-regimen-adjustment scope tracked here (IC 25-26-16). Ordinary dispensing under a pharmacist's base license needs no protocol at all. Note the instrument is a physician-adopted PROTOCOL rather than a negotiated bilateral agreement: IC 25-26-16-5(b) makes the physician 'the ultimate authority regarding the terms, implementation, revision, and renewal of the protocol,' subject only to a duty to consult a pharmacist. No filing with the Board of Pharmacy or PLA is required; the protocol is kept and produced on inspection.
Practice ownership (corporate practice of medicine)
Non-licensee ownership permitted — Indiana does not require pharmacist ownership of a pharmacy. Every pharmacy permit application must name a qualifying pharmacist who is in full responsible charge of the pharmacy's legal operation (IC 25-26-13-17 area; 856 IAC 1-7-4), but the ownership of the business itself is not licensee-restricted — the qualifying-pharmacist safeguard, not equity, is the control mechanism. Materially more permissive than the medical/APRN entity rules above. SECONDARY-SOURCED: this ownership point was confirmed via Board of Pharmacy guidance summaries rather than by reading IC 25-26-13-17's full current text.
Pharmacists are absent from IC 25-22.5-1-2(a)(22)'s health-care-organization ownership list, but that list governs exclusion from the MEDICAL Practice Act and is not the operative rule for pharmacy ownership.
Legal sources for these rules (4)
- IC 25-26-16 — Drug Regimens, full chapter incl. § 1 ('protocol'), § 2 ('adjusts'), § 3/§ 3.5 (authorization), § 4 (hospital minimums), § 4.5 (non-hospital protocol; 'direct supervision' definition), § 5 (physician as ultimate authority), § 6 (modification requires new protocol), § 7 (annual review), § 8 (documentation). Verbatim text from Justia's archived Indiana Code chapter PDF (2015 vintage), decoded locallysecondary
- IC 25-26-16-4.5 — Protocol for Pharmacists (FindLaw mirror, current as of 1/1/2026 — fetched specifically to confirm the archived chapter text above is still current; the current version's 'direct supervision' list reads 'advanced practice registered nurse,' reflecting Indiana's terminology update)secondary
- IC 25-26-13-31.2 — Administration of Immunizations by Pharmacists (not read in full in this pass; cited for the existence of a separate standing-order/protocol authority outside IC 25-26-16)
- 856 IAC 1-7-4 — Licensed Pharmacist Required for Each Pharmacy (Cornell LII Indiana Administrative Code mirror; basis for the qualifying-pharmacist point in `cpom`)secondary
What a collaborating physician costs here
Typical monthly cost in Indiana
$500 – $600
Estimate for one Pharmacist. Standard-tier state.
About Indiana's rules
Indiana requires a career-long collaborative practice agreement for every APRN role except CRNAs (IC 25-23-1-19.4(c)); APRN prescribers additionally face a codified 5%-of-charts random-sampling review (848 IAC 5-1-1). CRNAs instead face a stricter rule — physician direction and immediate presence (IC 25-23-1-30). Widely repeated reports that Indiana enacted full practice authority in 2026 are unsupported: HB 1116, HB 1129 and SB 60 all failed. Indiana's corporate-practice doctrine is comparatively permissive.
Other clinicians in Indiana: see the state overview.