NP · Florida

Collaborative Practice Agreement for Nurse Practitioners in Florida

Yes, a written physician agreement is required. Florida calls it a Written Protocol.

Practice authorityConditional independence
Written agreementAgreement required
What Florida calls itWritten Protocol
Governing boardFlorida Board of Nursing and the Florida Board of Pharmacy
Agreement familyCollaborative Practice
Research date2026-08-14 · clauses 2026-09-03

Autonomous-practice registration (§464.0123, enacted 2020) requires ≥3,000 supervised clinical hours within 5 years plus 3 semester hours each in differential diagnosis and pharmacology — but the resulting scope is limited to primary care (family medicine/general pediatrics/general internal medicine), not full APRN scope. Outside that scope, the standard established-protocol model applies.

Independent practice requires: ≥3,000 clinical practice hours under physician supervision, completed within the 5 years immediately preceding registration (§464.0123(1)); 3 graduate-level semester hours (or equivalent) in differential diagnosis, within the preceding 5 years; 3 graduate-level semester hours (or equivalent) in pharmacology, within the preceding 5 years; Active, unencumbered APRN license under §464.012; no disciplinary action under §456.072/§464.018 within the preceding 5 years; Registration with the Florida Board of Nursing (Fla. Admin. Code R. 64B9-4.020).

What the collaboration must look like

The rules the physician relationship has to follow. Each fact comes from the statute or board rule listed under sources.

Proximity

NP under established protocol (non-autonomous, or outside qualifying primary-care scope): No proximity requirement

No codified mileage/radius or on-site standard — the former protocol-standards rule (Fla. Admin. Code R. 64B9-4.010) has been repealed, with no successor rule found. Proximity/availability terms are left to be negotiated within each individual written protocol.

NP registered for autonomous practice under §464.0123, within qualifying primary-care scope: No proximity requirement

No physician relationship at all — practices without supervision or a protocol within the qualifying primary-care scope.

Supervision ratio

Not codified — no cap on file

Chart review

Not codified — left to the agreement

Meeting cadence

NP under established protocol (non-autonomous): As needed, in person or via telehealth

Not fixed by statute or rule — the Board of Nursing's official protocol template (floridasnursing.gov/forms/aprn-protocol-format.pdf) uses only generic language: parties 'share equally in the responsibility for reviewing treatment protocols as needed,' with the physician 'available by telephone or by other communication device when not physically available.' Actual cadence is whatever the individual protocol specifies.

Prescriptive authority

Covered by the practice agreement · controlled substances permitted

Folded into the same established protocol rather than requiring a separately-executed prescriptive-authority document, unlike Texas's PAA framework.

Written agreement

Required

Branches — autonomous-registered NPs (§464.0123) practicing within qualifying primary-care scope need no protocol at all. NPs outside that scope, or not yet registered, need an 'established protocol' (§464.012(3)) — Florida's statutory term, not 'collaborative practice agreement' — maintained on-site wherever the APRN practices.

Practice ownership (corporate practice of medicine)

Non-licensee ownership permitted — Same no-CPOM-doctrine framework as `pa` — §400.9905(4)(g)'s Health Care Clinic Act exemption explicitly names APRNs licensed under §464.012 among qualifying practitioner-owners, a stronger textual confirmation than found for PA specifically. An autonomous-registered NP practicing within qualifying primary-care scope may own and operate an entity entirely without physician involvement, in either the entity or the clinical relationship.

Legal sources for these rules (7)
The document: Written Protocol
What a Florida Written Protocol must contain, who governs it and who signs: read the Written Protocol page on practiceagreement.com.

What a collaborating physician costs here

Typical monthly cost in Florida

$500$600

Estimate for one Nurse Practitioner. Standard-tier state.

About Florida's rules

Florida's 2020 autonomous-practice law (§464.0123, ≥3,000 supervised hours + coursework) creates a real independence pathway for NP and CNM — but excludes PMHNP, CRNA, and CNS entirely; CRNA autonomy bills have died three sessions running (2024-2026). Florida has no corporate-practice-of-medicine doctrine (secondary-source consensus) — entity ownership instead turns on the Health Care Clinic Act's §400.9905 exemption mechanics. Supervision ratio/chart-review/meeting-cadence are largely uncodified; PA's 10-supervisee cap is the exception.

Other clinicians in Florida: see the state overview.